| Description | The persistence of an epidemic of obesity and type 2 diabetes suggeststhat new nutritional strategies are needed if the epidemic is tobe overcome. A promising nutritional approach suggested by thisthematic review is carbohydrate restriction. Recent studies showthat, under conditions of carbohydrate restriction, fuel sources shiftfrom glucose and fatty acids to fatty acids and ketones, and that adlibitum–fed carbohydrate-restricted diets lead to appetite reduction,weight loss, and improvement in surrogate markers of cardiovasculardisease. Am J Clin Nutr 2007;86:276–84. |